Araştırma Makalesi
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Yıl 2022, Cilt: 9 Sayı: 1, 49 - 64, 30.06.2022
https://doi.org/10.48138/cjo.994111

Öz

Destekleyen Kurum

Kafkas üniversitesi Bilimsel Araştırmalar Projesi

Kaynakça

  • Amirkhizi, F., Siassi, F., Djalali, M., & Shahraki, S. H. (2014). Impaired enzymatic antioxidant defense in erythrocytes of women with general and abdominal obesity. Obesity Research & Clinical Practice, 8(1), e26–e34. https://doi.org/10.1016/j.orcp.2012.07.004
  • Armstrong, T. A., Spears, J. W., & Lloyd, K. E. (2001). Inflammatory response, growth, and thyroid hormone concentrations are affected by long-term boron supplementation in gilts. Journal of Animal Science, 79(6), 1549. https://doi.org/10.2527/2001.7961549x
  • Aslan, M., Horoz, M., Sabuncu, T., Celik, H., & Selek, S. (2011). Serum paraoxonase enzyme activity and oxidative stress in obese subjects. Polish Archives of Internal Medicine, 121(6), 181–186. https://doi.org/10.20452/pamw.1051
  • Aviram, M., Rosenblat, M., Bisgaier, C. L., Newton, R. S., Primo-Parmo, S. L., & La Du, B. N. (1998). Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. Journal of Clinical Investigation, 101(8), 1581–1590. https://doi.org/10.1172/JCI1649
  • Basoglu, A., Sevinc, M., Guzelbektas, H., & Civelek, T. (2000). Effect of borax on serum lipid profile in dogs. Online Journal of Veterinary Research, 4, 153–156. https://www.cabdirect.org/cabdirect/abstract/20013122745
  • Bauer, C.-A., & Pettersson, G. (1974). Effect of Boric Acid on the Catalytic Activity of Streptomyces griseus Protease 3. European Journal of Biochemistry, 45(2), 473–477. https://doi.org/10.1111/j.1432-1033.1974.tb03572.x
  • Bentley, R. A., Ross, C. N., & O’Brien, Michael. J. (2018). Obesity, Metabolism, and Aging: A Multiscalar Approach. In Progress in Molecular Biology and Translational Science (Vol. 155, pp. 25–42). Elsevier. https://doi.org/10.1016/bs.pmbts.2017.11.016
  • Bolaños, L., Lukaszewski, K., Bonilla, I., & Blevins, D. (2004). Why boron? Plant Physiology and Biochemistry, 42(11), 907–912. https://doi.org/10.1016/j.plaphy.2004.11.002
  • Cakir, S., Eren, M., Senturk, M., & Sarica, Z. S. (2018). The Effect of Boron on Some Biochemical Parameters in Experimental Diabetic Rats. Biological Trace Element Research, 184(1), 165–172. https://doi.org/10.1007/s12011-017-1182-0
  • Chapin, R. E., Ku, W. W., Kenney, M. A., & McCoy, H. (1998). The effects of dietary boric acid on bone strength in rats. Biological Trace Element Research, 66(1–3), 395–399. https://doi.org/10.1007/BF02783150
  • Cui, Y., Winton, M. I., Zhang, Z.-F., Rainey, C., Marshall, J., De Kernion, J. B., & Eckhert, C. D. (2004). Dietary boron intake and prostate cancer risk. Oncology Reports, 11(4), 887–892.
  • de Almeida, M. M., Luquetti, S. C. P. D., Sabarense, C. M., Corrêa, J. O. do A., dos Reis, L. G., Conceição, E. P. S. da, Lisboa, P. C., de Moura, E. G., Gameiro, J., da Gama, M. A. S., Lopes, F. C. F., & Garcia, R. M. G. (2014). Butter naturally enriched in cis-9, trans-11 CLA prevents hyperinsulinemia and increases both serum HDL cholesterol and triacylglycerol levels in rats. Lipids in Health and Disease, 13(1), 200. https://doi.org/10.1186/1476-511X-13-200
  • Doğan, A., Demirci, S., Apdik, H., Bayrak, O. F., Gulluoglu, S., Tuysuz, E. C., Gusev, O., Rizvanov, A. A., Nikerel, E., & Şahin, F. (2017). A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism, 69, 130–142. https://doi.org/10.1016/j.metabol.2017.01.021
  • Dupre, J. N., Keenan, M. J., Hegsted, M., & Brudevold, A. M. (1994). Effects of dietary boron in rats fed a vitamin D-deficient diet. Environmental Health Perspectives, 102(suppl 7), 55–58. https://doi.org/10.1289/ehp.94102s755
  • Durrington, P. N., Mackness, B., & Mackness, M. I. (2001). Paraoxonase and Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 21(4), 473–480. https://doi.org/10.1161/01.ATV.21.4.473
  • Eckerson, H. W., Romson, J., Wyte, C., & La Du, B. N. (1983). The human serum paraoxonase polymorphism: Identification of phenotypes by their response to salts. American Journal of Human Genetics, 35(2), 214–227.
  • Fail, P. A., Chapin, R. E., Price, C. J., & Heindel, J. J. (1998). General, reproductive, developmental, and endocrine toxicity of boronated compounds. Reproductive Toxicology, 12(1), 1–18. https://doi.org/10.1016/S0890-6238(97)00095-6
  • Forster, J. L., Jeffery, R. W., Schmid, T. L., & Kramer, F. M. (1988). Preventing weight gain in adults: A pound of prevention. Health Psychology, 7(6), 515–525. https://doi.org/10.1037/0278-6133.7.6.515
  • Gan, K. N., Smolen, A., Eckerson, H. W., & La Du, B. N. (1991). Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities. Drug Metabolism and Disposition: The Biological Fate of Chemicals, 19(1), 100–106.
  • Garcia-Gonzalez, M., Mateo, P., & Bonilla, I. (1991). Boron Requirement for Envelope Structure and Function in Anabaena PCC 7119 Heterocysts. Journal of Experimental Botany, 42(7), 925–929. https://doi.org/10.1093/jxb/42.7.925
  • Ghiselli, A., Serafini, M., Natella, F., & Scaccini, C. (2000). Total antioxidant capacity as a tool to assess redox status: Critical view and experimental data. Free Radical Biology and Medicine, 29(11), 1106–1114. https://doi.org/10.1016/S0891-5849(00)00394-4
  • Hall, I. H., Spielvogel, B. F., Griffin, T. S., Docks, E. L., & Brotherton, R. J. (1989). The effects of boron hypolipidemic agents on LDL and HDL receptor binding and related enzyme activities of rat hepatocytes, aorta cells and human fibroblasts. Research Communications in Chemical Pathology and Pharmacology, 65(3), 297–317.
  • Huang, W., Liu, R., Ou, Y., Li, X., Qiang, O., Yu, T., & Tang, C.-W. (2013). Octreotide promotes weight loss via suppression of intestinal MTP and apoB48 expression in diet-induced obesity rats. Nutrition, 29(10), 1259–1265. https://doi.org/10.1016/j.nut.2013.01.013
  • Hunt, C. D. (1998). Regulation of enzymatic activity: One Possible Role of Dietary Boron in Higher Animals and Humans. Biological Trace Element Research, 66(1–3), 205–225. https://doi.org/10.1007/BF02783139
  • Hunt, C. D., Herbel, J. L., & Idso, J. P. (2009). Dietary boron modifies the effects of vitamin D3 nutrition on indices of energy substrate utilization and mineral metabolism in the chick. Journal of Bone and Mineral Research, 9(2), 171–182. https://doi.org/10.1002/jbmr.5650090206
  • Ince, S., Kucukkurt, I., Cigerci, I. H., Fatih Fidan, A., & Eryavuz, A. (2010). The effects of dietary boric acid and borax supplementation on lipid peroxidation, antioxidant activity, and DNA damage in rats. Journal of Trace Elements in Medicine and Biology, 24(3), 161–164. https://doi.org/10.1016/j.jtemb.2010.01.003
  • Karabal, E., Yücel, M., & Öktem, H. A. (2003). Antioxidant responses of tolerant and sensitive barley cultivars to boron toxicity. Plant Science, 164(6), 925–933. https://doi.org/10.1016/S0168-9452(03)00067-0
  • Kettner, C. A., & Shenvi, A. B. (1984). Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids. The Journal of Biological Chemistry, 259(24), 15106–15114.
  • Kucukkurt, I., Ince, S., Demirel, H. H., Turkmen, R., Akbel, E., & Celik, Y. (2015). The Effects of Boron on Arsenic-Induced Lipid Peroxidation and Antioxidant Status in Male and Female Rats. Journal of Biochemical and Molecular Toxicology, 29(12), 564–571. https://doi.org/10.1002/jbt.21729
  • Kurtoglu, V., Kurtoglu, F., & Akalin, P. P. (2018). The effects of various levels of boron supplementation on live weight, plasma lipid peroxidation, several biochemical and tissue antioxidant parameters of male mice**. Journal of Trace Elements in Medicine and Biology, 49, 146–150. https://doi.org/10.1016/j.jtemb.2018.05.013
  • Kuru, R., Yilmaz, S., Balan, G., Tuzuner, B. A., Tasli, P. N., Akyuz, S., Yener Ozturk, F., Altuntas, Y., Yarat, A., & Sahin, F. (2019). Boron-rich diet may regulate blood lipid profile and prevent obesity: A non-drug and self-controlled clinical trial. Journal of Trace Elements in Medicine and Biology, 54, 191–198. https://doi.org/10.1016/j.jtemb.2019.04.021
  • La Du, B. N., Aviram, M., Billecke, S., Navab, M., Primo-Parmo, S., Sorenson, R. C., & Standiford, T. J. (1999). On the physiological role(s) of the paraoxonases. Chemico-Biological Interactions, 119–120, 379–388. https://doi.org/10.1016/S0009-2797(99)00049-6
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  • Meneses, M. J., Silvestre, R., Sousa-Lima, I., & Macedo, M. P. (2019). Paraoxonase-1 as a Regulator of Glucose and Lipid Homeostasis: Impact on the Onset and Progression of Metabolic Disorders. International Journal of Molecular Sciences, 20(16), 4049. https://doi.org/10.3390/ijms20164049
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  • Murray, F. J. (1998). A comparative review of the pharmacokinetics of boric acid in rodents and humans. Biological Trace Element Research, 66(1–3), 331–341. https://doi.org/10.1007/BF02783146
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Investigation the Effect of Boric Acid effect on Antioxidant System, HDL Levels and PON Activity on Rats Feding to the High-Fat Diet

Yıl 2022, Cilt: 9 Sayı: 1, 49 - 64, 30.06.2022
https://doi.org/10.48138/cjo.994111

Öz

Recent studies have revealed that boron compounds can be effective in the treatment of obesity, which is known to be one of the most dangerous and complex health problems of this age. In this study, the therapeutic effect of boron molecules in the diet on obesity was investigated.
For this purpose, the effects of boron compounds on Total Antioxidant Status (TAS), Total Oxidant Status (TOS), High Density Lipoprotein (HDL) levels and paraoxanase (PON) activity were investigated in mice fed a high-fat diet.
The study material was 40 Sprague Dawley rats 4-5 months old with a mean live weight of 226.95 ± 5.75 g. Animals were divided into 4 groups as Group I (normal diet), Group II (High fat), Group III (High fat + Boric Acid) and Group IV (Boric Acid). Six weeks after the experiment, blood samples were taken from the animals and TAS, TOS, HDL levels and PON activity were measured from the samples. In addition, the live weight changes of the animals were recorded.
At the end of the study, we found that boric acid given in addition to drinking water did not significantly change TAS level and PON activity, but increased TOS and HDL levels. In addition, the weight average of the group treated with boric acid decreased.
As a result, boric acid did not have an effect on the antioxidant system, but it caused an increase in HDL level and a decrease in PON activity. In addition, boric acid can be effective in lowering body weight.

Kaynakça

  • Amirkhizi, F., Siassi, F., Djalali, M., & Shahraki, S. H. (2014). Impaired enzymatic antioxidant defense in erythrocytes of women with general and abdominal obesity. Obesity Research & Clinical Practice, 8(1), e26–e34. https://doi.org/10.1016/j.orcp.2012.07.004
  • Armstrong, T. A., Spears, J. W., & Lloyd, K. E. (2001). Inflammatory response, growth, and thyroid hormone concentrations are affected by long-term boron supplementation in gilts. Journal of Animal Science, 79(6), 1549. https://doi.org/10.2527/2001.7961549x
  • Aslan, M., Horoz, M., Sabuncu, T., Celik, H., & Selek, S. (2011). Serum paraoxonase enzyme activity and oxidative stress in obese subjects. Polish Archives of Internal Medicine, 121(6), 181–186. https://doi.org/10.20452/pamw.1051
  • Aviram, M., Rosenblat, M., Bisgaier, C. L., Newton, R. S., Primo-Parmo, S. L., & La Du, B. N. (1998). Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. Journal of Clinical Investigation, 101(8), 1581–1590. https://doi.org/10.1172/JCI1649
  • Basoglu, A., Sevinc, M., Guzelbektas, H., & Civelek, T. (2000). Effect of borax on serum lipid profile in dogs. Online Journal of Veterinary Research, 4, 153–156. https://www.cabdirect.org/cabdirect/abstract/20013122745
  • Bauer, C.-A., & Pettersson, G. (1974). Effect of Boric Acid on the Catalytic Activity of Streptomyces griseus Protease 3. European Journal of Biochemistry, 45(2), 473–477. https://doi.org/10.1111/j.1432-1033.1974.tb03572.x
  • Bentley, R. A., Ross, C. N., & O’Brien, Michael. J. (2018). Obesity, Metabolism, and Aging: A Multiscalar Approach. In Progress in Molecular Biology and Translational Science (Vol. 155, pp. 25–42). Elsevier. https://doi.org/10.1016/bs.pmbts.2017.11.016
  • Bolaños, L., Lukaszewski, K., Bonilla, I., & Blevins, D. (2004). Why boron? Plant Physiology and Biochemistry, 42(11), 907–912. https://doi.org/10.1016/j.plaphy.2004.11.002
  • Cakir, S., Eren, M., Senturk, M., & Sarica, Z. S. (2018). The Effect of Boron on Some Biochemical Parameters in Experimental Diabetic Rats. Biological Trace Element Research, 184(1), 165–172. https://doi.org/10.1007/s12011-017-1182-0
  • Chapin, R. E., Ku, W. W., Kenney, M. A., & McCoy, H. (1998). The effects of dietary boric acid on bone strength in rats. Biological Trace Element Research, 66(1–3), 395–399. https://doi.org/10.1007/BF02783150
  • Cui, Y., Winton, M. I., Zhang, Z.-F., Rainey, C., Marshall, J., De Kernion, J. B., & Eckhert, C. D. (2004). Dietary boron intake and prostate cancer risk. Oncology Reports, 11(4), 887–892.
  • de Almeida, M. M., Luquetti, S. C. P. D., Sabarense, C. M., Corrêa, J. O. do A., dos Reis, L. G., Conceição, E. P. S. da, Lisboa, P. C., de Moura, E. G., Gameiro, J., da Gama, M. A. S., Lopes, F. C. F., & Garcia, R. M. G. (2014). Butter naturally enriched in cis-9, trans-11 CLA prevents hyperinsulinemia and increases both serum HDL cholesterol and triacylglycerol levels in rats. Lipids in Health and Disease, 13(1), 200. https://doi.org/10.1186/1476-511X-13-200
  • Doğan, A., Demirci, S., Apdik, H., Bayrak, O. F., Gulluoglu, S., Tuysuz, E. C., Gusev, O., Rizvanov, A. A., Nikerel, E., & Şahin, F. (2017). A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism, 69, 130–142. https://doi.org/10.1016/j.metabol.2017.01.021
  • Dupre, J. N., Keenan, M. J., Hegsted, M., & Brudevold, A. M. (1994). Effects of dietary boron in rats fed a vitamin D-deficient diet. Environmental Health Perspectives, 102(suppl 7), 55–58. https://doi.org/10.1289/ehp.94102s755
  • Durrington, P. N., Mackness, B., & Mackness, M. I. (2001). Paraoxonase and Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 21(4), 473–480. https://doi.org/10.1161/01.ATV.21.4.473
  • Eckerson, H. W., Romson, J., Wyte, C., & La Du, B. N. (1983). The human serum paraoxonase polymorphism: Identification of phenotypes by their response to salts. American Journal of Human Genetics, 35(2), 214–227.
  • Fail, P. A., Chapin, R. E., Price, C. J., & Heindel, J. J. (1998). General, reproductive, developmental, and endocrine toxicity of boronated compounds. Reproductive Toxicology, 12(1), 1–18. https://doi.org/10.1016/S0890-6238(97)00095-6
  • Forster, J. L., Jeffery, R. W., Schmid, T. L., & Kramer, F. M. (1988). Preventing weight gain in adults: A pound of prevention. Health Psychology, 7(6), 515–525. https://doi.org/10.1037/0278-6133.7.6.515
  • Gan, K. N., Smolen, A., Eckerson, H. W., & La Du, B. N. (1991). Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities. Drug Metabolism and Disposition: The Biological Fate of Chemicals, 19(1), 100–106.
  • Garcia-Gonzalez, M., Mateo, P., & Bonilla, I. (1991). Boron Requirement for Envelope Structure and Function in Anabaena PCC 7119 Heterocysts. Journal of Experimental Botany, 42(7), 925–929. https://doi.org/10.1093/jxb/42.7.925
  • Ghiselli, A., Serafini, M., Natella, F., & Scaccini, C. (2000). Total antioxidant capacity as a tool to assess redox status: Critical view and experimental data. Free Radical Biology and Medicine, 29(11), 1106–1114. https://doi.org/10.1016/S0891-5849(00)00394-4
  • Hall, I. H., Spielvogel, B. F., Griffin, T. S., Docks, E. L., & Brotherton, R. J. (1989). The effects of boron hypolipidemic agents on LDL and HDL receptor binding and related enzyme activities of rat hepatocytes, aorta cells and human fibroblasts. Research Communications in Chemical Pathology and Pharmacology, 65(3), 297–317.
  • Huang, W., Liu, R., Ou, Y., Li, X., Qiang, O., Yu, T., & Tang, C.-W. (2013). Octreotide promotes weight loss via suppression of intestinal MTP and apoB48 expression in diet-induced obesity rats. Nutrition, 29(10), 1259–1265. https://doi.org/10.1016/j.nut.2013.01.013
  • Hunt, C. D. (1998). Regulation of enzymatic activity: One Possible Role of Dietary Boron in Higher Animals and Humans. Biological Trace Element Research, 66(1–3), 205–225. https://doi.org/10.1007/BF02783139
  • Hunt, C. D., Herbel, J. L., & Idso, J. P. (2009). Dietary boron modifies the effects of vitamin D3 nutrition on indices of energy substrate utilization and mineral metabolism in the chick. Journal of Bone and Mineral Research, 9(2), 171–182. https://doi.org/10.1002/jbmr.5650090206
  • Ince, S., Kucukkurt, I., Cigerci, I. H., Fatih Fidan, A., & Eryavuz, A. (2010). The effects of dietary boric acid and borax supplementation on lipid peroxidation, antioxidant activity, and DNA damage in rats. Journal of Trace Elements in Medicine and Biology, 24(3), 161–164. https://doi.org/10.1016/j.jtemb.2010.01.003
  • Karabal, E., Yücel, M., & Öktem, H. A. (2003). Antioxidant responses of tolerant and sensitive barley cultivars to boron toxicity. Plant Science, 164(6), 925–933. https://doi.org/10.1016/S0168-9452(03)00067-0
  • Kettner, C. A., & Shenvi, A. B. (1984). Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids. The Journal of Biological Chemistry, 259(24), 15106–15114.
  • Kucukkurt, I., Ince, S., Demirel, H. H., Turkmen, R., Akbel, E., & Celik, Y. (2015). The Effects of Boron on Arsenic-Induced Lipid Peroxidation and Antioxidant Status in Male and Female Rats. Journal of Biochemical and Molecular Toxicology, 29(12), 564–571. https://doi.org/10.1002/jbt.21729
  • Kurtoglu, V., Kurtoglu, F., & Akalin, P. P. (2018). The effects of various levels of boron supplementation on live weight, plasma lipid peroxidation, several biochemical and tissue antioxidant parameters of male mice**. Journal of Trace Elements in Medicine and Biology, 49, 146–150. https://doi.org/10.1016/j.jtemb.2018.05.013
  • Kuru, R., Yilmaz, S., Balan, G., Tuzuner, B. A., Tasli, P. N., Akyuz, S., Yener Ozturk, F., Altuntas, Y., Yarat, A., & Sahin, F. (2019). Boron-rich diet may regulate blood lipid profile and prevent obesity: A non-drug and self-controlled clinical trial. Journal of Trace Elements in Medicine and Biology, 54, 191–198. https://doi.org/10.1016/j.jtemb.2019.04.021
  • La Du, B. N., Aviram, M., Billecke, S., Navab, M., Primo-Parmo, S., Sorenson, R. C., & Standiford, T. J. (1999). On the physiological role(s) of the paraoxonases. Chemico-Biological Interactions, 119–120, 379–388. https://doi.org/10.1016/S0009-2797(99)00049-6
  • Liu, W., Wang, H., Wang, Y., Li, H., & Ji, L. (2015). Metabolic factors-triggered inflammatory response drives antidepressant effects of exercise in CUMS rats. Psychiatry Research, 228(3), 257–264. https://doi.org/10.1016/j.psychres.2015.05.102
  • Meneses, M. J., Silvestre, R., Sousa-Lima, I., & Macedo, M. P. (2019). Paraoxonase-1 as a Regulator of Glucose and Lipid Homeostasis: Impact on the Onset and Progression of Metabolic Disorders. International Journal of Molecular Sciences, 20(16), 4049. https://doi.org/10.3390/ijms20164049
  • Moylan, J. S., & Reid, M. B. (2007). Oxidative stress, chronic disease, and muscle wasting. Muscle & Nerve, 35(4), 411–429. https://doi.org/10.1002/mus.20743
  • Murakami, J. M., Essayli, J. H., & Latner, J. D. (2016). The relative stigmatization of eating disorders and obesity in males and females. Appetite, 102, 77–82. https://doi.org/10.1016/j.appet.2016.02.027
  • Murray, F. J. (1998). A comparative review of the pharmacokinetics of boric acid in rodents and humans. Biological Trace Element Research, 66(1–3), 331–341. https://doi.org/10.1007/BF02783146
  • Naghii, M. R., & Samman, S. (1997). The effect of boron supplementation on its urinary excretion and selected cardiovascular risk factors in healthy male subjects. Biological Trace Element Research, 56(3), 273–286. https://doi.org/10.1007/BF02785299
  • Olusi, S. (2002). Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotectic enzymes in humans. International Journal of Obesity, 26(9), 1159–1164. https://doi.org/10.1038/sj.ijo.0802066
  • Ozata, M., Mergen, M., Oktenli, C., Aydin, A., Yavuz Sanisoglu, S., Bolu, E., Yilmaz, M. I., Sayal, A., Isimer, A., & Ozdemir, I. C. (2002). Increased oxidative stress and hypozincemia in male obesity. Clinical Biochemistry, 35(8), 627–631. https://doi.org/10.1016/S0009-9120(02)00363-6
  • Piva, S. J., Duarte, M. M. M. F., Da Cruz, I. B. M., Coelho, A. C., Moreira, A. P. L., Tonello, R., Garcia, S. C., & Moresco, R. N. (2011). Ischemia-modified albumin as an oxidative stress biomarker in obesity. Clinical Biochemistry, 44(4), 345–347. https://doi.org/10.1016/j.clinbiochem.2010.12.001
  • Primo-Parmo, S. L., Sorenson, R. C., Teiber, J., & Du, B. N. L. (1996). The Human Serum Paraoxonase/Arylesterase Gene (PON1) Is One Member of a Multigene Family. Genomics, 33(3), 498–507. https://doi.org/10.1006/geno.1996.0225
  • Roh, H.-T., & So, W.-Y. (2017). The effects of aerobic exercise training on oxidant–antioxidant balance, neurotrophic factor levels, and blood–brain barrier function in obese and non-obese men. Journal of Sport and Health Science, 6(4), 447–453. https://doi.org/10.1016/j.jshs.2016.07.006
  • Roy, A., Chardigny, J.-M., Bauchart, D., Ferlay, A., Lorenz, S., Durand, D., Gruffat, D., Faulconnier, Y., Sébédio, J.-L., & Chilliard, Y. (2007). Butters rich either in trans -10-C18:1 or in trans -11-C18:1 plus cis -9, trans -11 CLA differentially affect plasma lipids and aortic fatty streak in experimental atherosclerosis in rabbits. Animal, 1(3), 467–476. https://doi.org/10.1017/S175173110770530X
  • Sharma, A., Mani, V., Pal, R. P., Sarkar, S., & Datt, C. (2020). Boron supplementation in peripartum Murrah buffaloes: The effect on calcium homeostasis, bone metabolism, endocrine and antioxidant status. Journal of Trace Elements in Medicine and Biology, 62, 126623. https://doi.org/10.1016/j.jtemb.2020.126623
  • Shuler, T. R. (1990). Effect of thalassemia/hemoglobin E disease on macro, trace, and ultratrace element concentrations in human tissue (T. R. Shuler, P. Pootrakul, P. Yarnsukon, & F. H. Nielsen, Trans.). Journal of Trace Elements in Experimental Medicine, v. 3, 31–43. PubAg.
  • Sorenson, R. C., Primo-Parmo, S. L., Kuo, C. L., Adkins, S., Lockridge, O., & La Du, B. N. (1995). Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase. Proceedings of the National Academy of Sciences, 92(16), 7187–7191. https://doi.org/10.1073/pnas.92.16.7187
  • Sutherland, B., Strong, P., & King, J. C. (1998). Determining human dietary requirements for boron. Biological Trace Element Research, 66(1–3), 193–204. https://doi.org/10.1007/BF02783138
  • Tabur, S., Torun, A. N., Sabuncu, T., Turan, M. N., Celik, H., Ocak, A. R., & Aksoy, N. (2010). Non-diabetic metabolic syndrome and obesity do not affect serum paraoxonase and arylesterase activities but do affect oxidative stress and inflammation. European Journal of Endocrinology, 162(3), 535–541. https://doi.org/10.1530/EJE-09-0732
  • Tanaka, M., & Fujiwara, T. (2008). Physiological roles and transport mechanisms of boron: Perspectives from plants. Pflügers Archiv - European Journal of Physiology, 456(4), 671–677. https://doi.org/10.1007/s00424-007-0370-8
  • Türkez, H., Geyikoǧlu, F., Tatar, A., Keleş, S., & Özkan, A. (2007). Effects of Some Boron Compounds on Peripheral Human Blood. Zeitschrift Für Naturforschung C, 62(11–12), 889–896. https://doi.org/10.1515/znc-2007-11-1218
  • U.S. Environmental Protection Agency. (n.d.). Toxicological Review of Boron And Compounds, CAS No. 7440-42-8. Cfpub.Epa.Gov. Retrieved 10 March 2020, from https://cfpub.epa.gov/ncea/iris/iris_documents/documents/toxreviews/0410tr.pdf
  • Woods, W. G. (1994). An introduction to boron: History, sources, uses, and chemistry. Environmental Health Perspectives, 102(suppl 7), 5–11. https://doi.org/10.1289/ehp.94102s75
  • Yildiz, G., Koksal, B. H., & Sizmaz, O. (2013). Effects of dietary boric acid addition on growth performance, cholesterolemia, some carcass and tibia characteristics in different rearing periods in broiler chickens. Revue Méd. Vét., 6.
Toplam 54 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çevre Bilimleri
Bölüm Caucasian Journal of Science
Yazarlar

Destan Kalaçay 0000-0002-3921-5549

Onur Atakisi 0000-0003-1183-6076

Yayımlanma Tarihi 30 Haziran 2022
Gönderilme Tarihi 13 Eylül 2021
Kabul Tarihi 21 Haziran 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 9 Sayı: 1

Kaynak Göster

APA Kalaçay, D., & Atakisi, O. (2022). Investigation the Effect of Boric Acid effect on Antioxidant System, HDL Levels and PON Activity on Rats Feding to the High-Fat Diet. Caucasian Journal of Science, 9(1), 49-64. https://doi.org/10.48138/cjo.994111

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