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Mikrobiyotanın Kadın ve Çocuk Sağlığına Etkisi

Year 2020, Volume: 36 Issue: 3, 207 - 216, 28.12.2020

Seher Durğut Yurdagül Yağmur

Abstract

İnsan vücudunda virüs, bakteri ve mantar gibi mikrobiyal türlerden oluşan tüm mikroorganizmalar mikrobiyota olarak adlandırılır. İnsan mikrobiyomu sağlığın korunmasında rol oynar, fakat aynı zamanda mikrobiyal türlerdeki belirli değişimlerin anne-çocuk sağlığını olumsuz etkilediği düşünülmektedir. Mikrobiyota gelişimi uterin ortamda başlar ancak doğum şekli, vajinal ortam, gebelikte antibiyotik ve probiyotik kullanımı, yaşam tarzı gibi faktörlerin yeni doğan mikrobiyomunun ilk kolonizasyon sürecini etkilediği gösterilmiştir. Son yapılan çalışmalarla birlikte yaşamın ilk yıllarından itibaren oluşan mikrobiyal kolonizasyonun, kadın hayatının tüm dönemlerinde hastalık/ sağlık durumunu etkilediği düşünülmektedir. Bu derlemenin amacı mikrobiyotanın kadın ve çocuk sağlığı üzerine etkisini değerlendirmektir.

Keywords

Mikrobiyota kadın sağlığı

References

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  • Alyamaç Dizdar, E. (2017). Anne sütünün alerjik hastalıkların gelişimine etkisi. Türk Dünyası Uygulama ve Araştırma Merkezi Yenidoğan Dergisi, 1000 Gün, Anne Sütü Kursu, 209- 217. Erişim adresi: https://dergipark.org.tr/en/download/article-file/751754
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  • Bäckhed, F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., …Wang, J. (2015). Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe, 17(5), 690-703. doi: 10.1016 / j.chom.
  • Boix-Amorós, A., Collado, M. C., Mira, A. (2016). Relationship between milk microbiota, bacterial load, macronutrients, and human cells during lactation. Frontiersin Microbiology, 7, (492). doi: 10.3389 / fmicb.2016.00492.
  • Brooks, J. L., Edwards, D. J., Blithe, D. L., Fettweis, J. M., Serrano, M. G., Sheth, N. U., … Jefferson, K. K. (2017). Effects of combined oral contraceptives, depot medroxyprogesterone acetate and the levonorgestrel-releasing intrauterine system on the vaginal microbiome. American Journal of Obstetrics & Gynecology, 95(4), 405–413. doi: 10.1016 / j.contraception.2016.11.006.
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Year 2020, Volume: 36 Issue: 3, 207 - 216, 28.12.2020

Seher Durğut Yurdagül Yağmur

Abstract

References

  • KAYNAKLAR Achilles, S. L., Austin, M. N., Meyn, L. A., Mhlanga, F., Chirenje, Z. M., Hillier, S. L. (2018). Impact of contraceptive initiation on vaginal microbiota. American Journal of Obstetrics & Gynecology, 218 (622), 1- 10. doi: 10.1016 / j.ajog.
  • Alyamaç Dizdar, E. (2017). Anne sütünün alerjik hastalıkların gelişimine etkisi. Türk Dünyası Uygulama ve Araştırma Merkezi Yenidoğan Dergisi, 1000 Gün, Anne Sütü Kursu, 209- 217. Erişim adresi: https://dergipark.org.tr/en/download/article-file/751754
  • Amabebe, E., Anumba, D. O. C. (2018). The vaginal microenvironment: the physiologic role of lactobacilli. Frontiers in Medicine, 5(181). doi: 10.3389 / fmed
  • Bäckhed, F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., …Wang, J. (2015). Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe, 17(5), 690-703. doi: 10.1016 / j.chom.
  • Boix-Amorós, A., Collado, M. C., Mira, A. (2016). Relationship between milk microbiota, bacterial load, macronutrients, and human cells during lactation. Frontiersin Microbiology, 7, (492). doi: 10.3389 / fmicb.2016.00492.
  • Brooks, J. L., Edwards, D. J., Blithe, D. L., Fettweis, J. M., Serrano, M. G., Sheth, N. U., … Jefferson, K. K. (2017). Effects of combined oral contraceptives, depot medroxyprogesterone acetate and the levonorgestrel-releasing intrauterine system on the vaginal microbiome. American Journal of Obstetrics & Gynecology, 95(4), 405–413. doi: 10.1016 / j.contraception.2016.11.006.
  • Coulam, C. B., Bilal, M., Maria, D., Garcia, S., Katukurundage, D., Elazızı, H., … Dambaeva, S. V. (2018). Prevalence of HHV‐6 in endometrium from women with recurrent implantation failure. American Journal of Reproductive Immınology. doi: 10.1111 / aji.12862.
  • Çetinbaş, A. (2017). Mikrobiyota. Eurasian Journal of Family Medicine, 6(2), 51-56. Erişim adresi: http://ejfm.trakya.edu.tr/userfiles/2017/August/1-ayca-cetinbas.pdf.
  • De Castro-Sobrinho, J. M., Rabelo-Santos, S. H., Fugueiredo-Alves, R. R., Derchain, S., Sarian, L. O., Pitta, D. R., … Zeferino L.C. (2016). Bacterial vaginosis and inflammatory response showed association with severity of cervical neoplasia in HPV-Positive women. Diagnostic Cytopathology, 44(2), 80– 86. doi: 10.1002 / dc.23388.
  • De Freitas, A. S., Thiago Dobbler, P. C., Mai, V., Procianoy, R. S., Silveira, R. C., Corso, A. L., Wurdig Roesch, L. F. (2019). Defining microbial biomarkers for risk of preterm labor. Brazilian Journal of Microbiology, 1-9. doi: https://doi.org/10.1007/s42770-019-00118-x.
  • Demirok, N. T. (2014). Bebeklerden izole edilen lactobacillus spp.’nin fonksiyonel özelliklerinin belirlenmesi. (Doktora Tezi). Namık Kemal Üniversitesi, Fen Bilimleri Enstitüsü, Tekirdağ.
  • Di Paola, M., Sani, C., Clemente, A. M., Iossa, A., Perissi, E., Castronovo, G., … Gabriella Torcia, M. (2017). Characterization of cervico-vaginal microbiota in women developing persistent high-risk human papillomavirus infection. Scientific Reports, 7, 10200. https://doi.org/10.1038/s41598-017-09842-6
  • Donders Ghislain, G. G., Bellen, G., Ruban, K., Bulck, B. V. (2018). Short- and long-term influence of the levonorgestrel-releasing intrauterine system (Mirena®) on vaginal microbiota and candida. Journal of Medical Microbiology, 67, 308–313. https://doi.org/10.1099/jmm.0.000657
  • Dunn, A. B., Jordan, S., Baker, B. J., Carlson, N. S. (2017). The maternal ınfant microbiome: considerations for labor and birth. MCN The American Journal of Maternal Child Nursing, 42(6), 318–325. doi: 10.1097 / NMC.0000000000000373.
  • Erbay, E., Topal, S., Altınkaynak, S. (2019).” Yaşama Sağlıklı Başlamanın Basamakları”. Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi, 22(1), 64-70. Erişim adresi: https://dergipark.org.tr/tr/download/article-file/687767
  • Evrensel, A., Ceylan, M. (2015). Bağırsak beyin ekseni: psikiyatrik bozukluklarda bağırsak mikrobiyotasının rolü. Psikiyatride Güncel Yaklaşımlar, 7(4), 461-472. doi: 10.5455/cap.20150128123852.
  • Flores, R., Shi, J., Fuhrman, B., Xu, X., Veenstra, T. D., Gail, M. H., Gajer, P., … Goedert, J. J. (2012). Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: A cross-sectional study. Journal of Translational Medicine, 10, 253. doi: 10.1186 / 1479-5876-10-253.
  • Gabriella Torcia, M. (2019). Interplay among vaginal microbiome, ımmune response and sexually transmitted viral ınfections. International Journal of Molecular Sciences, 20(2), 266. doi: 10.3390 / ijms20020266
  • Gao, W., Weng, J., Gao, Y., Chen, X. (2013). Comparison of the vaginal microbiota diversity of women with and without human papillomavirus infection: a cross-sectional study”. BMC Infectious Diseases, 13(271), 1-10 . doi: 10.1186 / 1471-2334-13-271.
  • García-Velasco, J.A., Menabrito, M., Catalán, I. B. (2017). What fertility specialists should know about the vaginal microbiome: a review”. Reproductive BioMedicine Online, 1-10. doi: https://doi.org/10.1016/j.rbmo.2017.04.005.
  • Gosmann, C., Anahtar, M. N., Handley, S. A., Farcasanu, M., Abu-Ali, G., Bowman, B. A., … Kwon. D. S. (2017). Lactobacillus-deficient cervicovaginal bacterial communities are associated with ıncreased HIV acquisition in young south african women. Immunity, 46(1),29-37. doi: 10.1016 / j.immuni.
  • Guo, Y. Y. K., Qiao, J., Zhao, Y., Geng, L. (2012). Bacterial vaginosis is conducive to the persistence of HPV infection. International Journal of STD and AIDS, 23, 581–4. doi: 10.1258 / ijsa.2012.011342.
  • Güney, R., Çınar, N. (2017). Anne sütü ve mikrobiyota gelişimi. Journal Biotechnol and Strategic Health Res, 1, 17-24. Erişim adresi: https://dergipark.org.tr/tr/download/article-file/377371.
  • Huang, B., Fettweis, J. M., Brooks, J. P., Jefferson, K. K., Buck, G. A . (2014). The changing landscape of the vaginal microbiome. Clinics in Laboratory Medicine, 34 (4), 747–761. doi: 10.1016 / j.cll.2014.08.006.
  • Hurley, E., Mullins, D., Barrett, M. P., O’Shea, C. A., Kinirons M., Ryan, C. A., … O’Toole, P. W. (2019). The microbiota of the mother at birth and its influence on the emerging infant oral microbiota from birth to 1 year of age: a cohort study. Journal of Oral Microbiology, 11 (1). doi: :10.1080/20002297.2019.1599652.
  • Keet, E. (2017). Synbiotic treatment significantly reduces ınfant sepsis deaths in India. Contagion Live Infectious Diseases Today. Erişim adresi: https://www.contagionlive.com/news/synbiotic-treatment-significantly-reduces-infant-sepsis-deaths-in-india.
  • Kılıç, Ü., Altındiş, M. (2017). Antibiyotik kullanımı ve mikrobiyota. Journal Biotechnology and Strategic Health Res, 1, 39-43. Erişim adresi: https://dergipark.org.tr/tr/download/article-file/377445.
  • Kim, J. M., Park, Y. J. (2017). Probiotics in the prevention and treatment of postmenopausal vaginal ınfections: review article. Journal of Menopausal Medicine, 23, 139-145. doi: 10.6118 / jmm.2017.23.3.139.
  • Kindinger, L. M., Macintyre, D. A., Lee, Y. S., Marchesi, J. R., Smith, A., McDonald, J. A. K. (2016). Relationship between vaginal microbial dysbiosis, inflammation and pregnancy outcomes in cervical cerclage. Science Translational Medicine, 8(350). doi: http://dx.doi.org/10.1126/scitranslmed.aag1026.
  • Klatt, N. R., Canary, L. A., Sun, X., Vinton, C. L., Funderburg, N. T., Morcock, D. R., … Brenchley, J. M. (2013). Probiotic/Prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. The Journal of Clinical Investigation, 123(2), 903-7. doi: 10.1172/JCI66227.
  • Koçak, T., Şanlı Er, N. (2017). Mikrobesin öğeleri ve mikrobiyota etkileşimi. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, 6(4), 290-302. Erişim adresi: https://dergipark.org.tr/tr/pub/gumussagbil/issue/32215/370460
  • Koedooder, R., Singer, M., Schoenmakers, S., Savelkoul, P. H. M., Morré, S. A., Jonge, J.D., … Laven, J. S. E. (2019). The vaginal microbiome as a predictor for outcome of in vitro fertilization with or without intracytoplasmic sperm injection: A prospective study. Human Reproduction, 34 (6), 1042–1054. doi: 10.1093 / humrep / dez065.
  • Kristensen, K., Henriksen, L. (2016). Cesarean section and disease associated with immune function. Journal of Allergy and Clinical Immunology, 137(2), 587–590. doi: https://doi.org/10.1016/j.jaci.2015.07.040.
  • Kroon, S. J., Ravel, J., Huston, W. M. (2018). Cervicovaginal microbiota, women's health and reproductive outcomes. Fertilty and Sterility, 110(3), 327–336. doi: 10.1016 / j.fertnstert.2018.06.036.
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Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Derlemeler
Authors

Seher Durğut 0000-0003-0730-1968

Yurdagül Yağmur 0000-0001-7798-6515

Publication Date December 28, 2020
Submission Date March 17, 2020
Acceptance Date July 2, 2020
Published in Issue Year 2020 Volume: 36 Issue: 3

Cite

APA Durğut, S., & Yağmur, Y. (2020). Mikrobiyotanın Kadın ve Çocuk Sağlığına Etkisi. Ege Üniversitesi Hemşirelik Fakültesi Dergisi, 36(3), 207-216.
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